25/09/2021
Chelsea	18:30	Manchester City
Manchester United	18:30	Aston Villa
Everton	21:00	Norwich City
Leeds United	21:00	West Ham United
Leicester City	21:00	Burnley
Watford	21:00	Newcastle United
Brentford	23:30	Liverpool
26/09/2021
Southampton	20:00	Wolverhampton Wanderers
Arsenal	22:30	Tottenham Hotspur
28/09/2021
Crystal Palace	02:00	Brighton & Hov…
02/10/2021
Manchester United	18:30	Everton
Wolverhampton Wanderers	21:00	Newcastle United
Burnley	21:00	Norwich City
Leeds United	21:00	Watford
Chelsea	21:00	Southampton
Brighton & Hov…	23:30	Arsenal
03/10/2021
Crystal Palace	20:00	Leicester City
Tottenham Hotspur	20:00	Aston Villa
West Ham United	20:00	Brentford
Liverpool	22:30	Manchester City